Clinical Trials Detalhe
A Phase 3 Trial of ALIMTA (LY231514, Pemetrexed) Plus GEMZAR Versus GEMZAR in Patients With Unresectable or Metastatic Cancer of the Pancreas.
General Information
Gender
ALL
Age
N/A
Phase
PHASE3
Study Type
INTERVENTIONAL
Location
Lisbon, Portugal
Porto, Portugal
Santa Maria da Feira, Portugal
Santarém, Portugal
Clinicaltrial.gov
https://classic.clinicaltrials.gov/ct2/show/NCT00035035Summary
Definition: This study will compare the drug GEMZAR to a combination of GEMZAR plus ALIMTA for the treatment of cancer of the pancreas. Patients may be able to participate in this study if they have cancer in their pancreas that cannot be removed by surgery OR that has spread to a new site in their body.
Conditions
Pancreatic Neoplasms
Metastases, Neoplasm
Eligibility
Inclusion Criteria: * Pancreas cancer that cannot be removed by surgery OR that has spread to a new site in your body. * You must have one tumor that can be physically measured or scanned by the doctor. * You have not had any chemotherapy, immunotherapy, biologic therapy, or hormonal therapy for pancreas cancer, including 5-FU. * You cannot have any radiation for 4 weeks before starting this study, and you cannot have radiation to the whole pelvis. Exclusion Criteria: * Treatment with any medication or device that has not been approved by regulatory agencies, like the FDA, at the time you enter the study. * Documentation that the cancer has spread to your brain. * Pregnant or breastfeeding. * A second primary cancer. * Unable to stop aspirin or non-steroidal anti-inflammatory agents (like ibuprofen) for 5-8 days.